ZYRTEC®-D Tablets

ZYRTEC®-D Tablets

The proven allergy relief of ZYRTEC® plus a powerful decongestant.

Find it behind the pharmacy counter. No prescription needed.*


Temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:


Itchy, watery eyes

Runny nose

Itchy throat or nose

Nasal congestion

Reduces swelling of nasal passages. Temporarily relieves sinus congestion and pressure. Temporarily restores freer breathing through the nose.


Do not break or chew tablet; swallow tablet whole.
Adults and children 12 years and over:
Take 1 tablet every 12 hours; do not take more than 2 tablets in 24 hours.
Adults 65 years and over:
Ask a doctor.
Children under 12 years of age:
Ask a doctor.
Consumers with liver or kidney disease:
Ask a doctor.
Other information:
Store between 20° to 25°C (68° to 77°F).


Do not use:
  • if you have ever had an allergic reaction to this product or any of its ingredients or to an antihistamine containing hydroxyzine
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product
Ask a doctor before use if you have:
  • heart disease
  • thyroid disease
  • diabetes
  • glaucoma
  • high blood pressure
  • trouble urinating due to an enlarged prostate gland
  • liver or kidney disease. Your doctor should determine if you need a different dose.
Ask a doctor or pharmacist before use if you are taking tranquilizers or sedatives.
When using this product:
  • do not use more than directed
  • drowsiness may occur
  • avoid alcoholic drinks
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • be careful when driving a motor vehicle or operating machinery
Stop use and ask a doctor if:
  • an allergic reaction to this product occurs. Seek medical help right away
  • you get nervous, dizzy, or sleepless
  • symptoms do not improve within 7 days or are accompanied by fever
If pregnant or breast-feeding:
  • if breast-feeding: not recommended
  • if pregnant: ask a health professional before use
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)


Active ingredients (in each extended release tablet): Cetirizine HCl 5 mg, Pseudoephedrine HCl 120 mg
Purpose: Antihistamine, nasal decongestant
Inactive ingredients: Colloidal silicon dioxide, croscarmellose sodium, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide


FAQs about the switch
Is prescription ZYRTEC® still available?

Prescription ZYRTEC® is no longer available. ZYRTEC® is available over the counter (OTC) where other OTC medications are sold.

FAQs about ZYRTEC®
What is over-the-counter ZYRTEC®?

Over-the-counter ZYRTEC® is a medicine that provides effective, 24-hour relief of indoor and outdoor allergy symptoms. ZYRTEC® had been available by prescription for years, but since January 2008, it is available over the counter.

Is the OTC version of ZYRTEC® (cetirizine HCl) the same as the Rx strength?

Yes, OTC ZYRTEC® is the same strength once available only by prescription. You can count on OTC ZYRTEC® for effective 24-hour relief.

What symptoms does ZYRTEC® relieve?

ZYRTEC® (cetirizine HCl) relieves runny nose, sneezing, itchy nose or throat and itchy, watery eyes due to indoor and outdoor allergies. ZYRTEC-D® Tablets provide the added benefit of relieving nasal congestion.

How long will it take before I can expect relief with ZYRTEC®?

ZYRTEC® (cetirizine HCl) begins to work in as little as 1 hour and provides effective 24-hour relief.

FAQs for Responsible Dosing
What are some tips for dosing my child responsibly?

It is important to always read and follow label instructions. Always use the exact dosage specified on the label.
Always use the measuring device that comes with the medicine. Other items like kitchen teaspoons may not be accurate. Never use spoons, droppers or cups that come with other medicines.
If you have additional questions regarding treating your child's allergies, please speak with a doctor.

FAQs about Disposing of Unused Medicine
What is the proper way to dispose of unused or expired medicines?

Unless instructed otherwise, do not dispose of medicines by emptying them into your sink, toilet or storm drain.
Some states may have regulations regarding pharmacy or community take-back programs in which they may receive and dispose of returned unused drugs for patients. Please contact your local pharmacy or local authority to determine if it participates in such programs.
If medicines cannot be disposed of by take-back programs, place them in an unrecognizable sealed container and dispose of the container in your household trash.

Where can I learn more about proper medicine disposal?

Please visit: www.fda.gov/forconsumers/consumerupdates/ucm101653.htm for more information.

FAQs about Allergies
How do I know if I have allergies?

If you sneeze a lot or have a consistent runny or stuffy nose, there's a good chance you have upper respiratory allergies. Allergies affect more than 50 million people in the United States alone.

What are some common upper respiratory allergy symptoms?

People with allergies often experience sneezing, runny nose, stuffy nose (nasal congestion) or itchy, watery eyes.

How many types of upper respiratory allergies are there and what's the difference?

If your symptoms occur only at certain times of the year, chances are it’s seasonal allergic rhinitis, or outdoor allergies. Common triggers (substances that cause an allergic response) include tree, grass and weed pollens, or mold.
If your symptoms are year-round, it’s probably perennial allergic rhinitis, or indoor allergies. Common triggers include animal dander (tiny skin flakes or saliva from animals), indoor mold and dust mites.

What can I do to alleviate my indoor upper respiratory allergy symptoms?
  • Keep windows closed and use air conditioning.
  • Stay indoors during peak pollen hours: usually 5 am to 10 am.
  • Change your clothes after you’ve been outside.
  • Don’t hang laundry outside to dry.
  • Avoid mowing the lawn or raking leaves.